Semax

What is Semax?

Semax is a lab-made peptide of seven amino acids (Met-Glu-His-Phe-Pro-Gly-Pro). It is built from a piece of ACTH, the stress hormone, but the piece used (positions 4 to 7) has no hormonal effect. A Pro-Gly-Pro tail protects it from breakdown.

It was developed at the Institute of Molecular Genetics in Moscow and is used in Russia as a nasal drop. Elsewhere it is a research compound.

How does Semax work?

• BDNF: in rats it raised BDNF and its receptor, TrkB, in the hippocampus. BDNF helps nerve cells grow and form new connections.
• Nerve growth factors: it changes NGF and BDNF gene activity over hours in several brain areas.
• Brain protection: in rats with blocked blood flow to the brain, it shifted brain proteins toward protection.

What do researchers study it for?

• Memory and learning models
• Stroke and brain-injury models
• BDNF and neuroplasticity
• Comparisons and pairings with Selank, its sister peptide

Disclaimer:
All products on this site are for Research, Development use only. Products are Not for Human use of any kind. The statements made within this website have not been evaluated by the US Food and Drug Administration. The statements and the products of this company are not intended to diagnose, treat, cure or prevent any disease.