KPV

What is KPV?

KPV is a peptide of just three amino acids: lysine, proline and valine. It is the last three amino acids of alpha-MSH, a hormone best known for skin colour. KPV keeps much of alpha-MSH’s anti-inflammatory activity without its colour effects.

How does KPV work?

• Into the cell: in gut studies it entered cells through PepT1, a transporter that carries small peptides.
• Inflammation signals: inside cells it lowered NF-kB and MAP kinase signalling, two main switches for inflammation.
• Gut models: in mice with colitis it reduced inflammation, including when it was given by mouth.

What do researchers study it for?

• Gut inflammation and colitis models
• Skin and wound inflammation
• Delivery research, such as nanoparticles that carry KPV to the colon
• Blends, as the fourth peptide in KLOW

Disclaimer:
All products on this site are for Research, Development use only. Products are Not for Human use of any kind. The statements made within this website have not been evaluated by the US Food and Drug Administration. The statements and the products of this company are not intended to diagnose, treat, cure or prevent any disease.